This is not a beach trip: pack for temperature swings and altitude, plus a season-dependent note on rain gear.
Pack in layers rather than for one temperature: mornings and evenings run cool at this altitude even when afternoons are warm, in any season. Add waterproof shoes and a compact umbrella if you are visiting during the rainy season, roughly May through October. Mexico runs on 127V/60Hz, essentially the same as the US's 120V/60Hz, using the same Type A and Type B plugs, so no adapter is needed, though a power bank helps on long excursion days. Keep any essential prescription medication in your carry-on rather than checked luggage; everyday pharmacy items are easy to buy locally once you arrive.
Mexico City sits above 7,300 feet, and that altitude does more to your packing list than the season does. Mornings and evenings run cool here across every season, so the real skill is layering, not picking one outfit for “Mexico.” Rain gear is the one thing that genuinely depends on when you’re visiting.
Visiting in the dry season instead, roughly November–April? Nothing extra required, just skip the rain gear above.
See The Best Time to Visit Mexico City for the month-by-month breakdown, but broadly: the dry season runs roughly November through April, cooler and clearer, while the rainy season runs May through October, warmer with dependable afternoon showers rather than all-day rain. Check which one your trip falls into before you pack, since it changes what actually earns a spot in your bag.
The altitude is the reason a single day here can swing from a cool, jacket-worthy morning to a warm early afternoon and back to a cool evening, regardless of season. A light jacket or fleece you can shed and stuff in a bag does more work here than any single “right” outfit. Breathable layers underneath beat one heavy layer, since you’ll be adding and removing them more than once a day.
Sunscreen is worth packing for the same reason, even though it rarely feels necessary in the moment. The UV index runs high at this elevation, but much of the city center sits under mature, leafy trees that shade entire streets, which masks how much sun you’re actually getting until the end of the day.
During the rainy season, afternoon downpours are dependable enough to plan around rather than hope to avoid, and cobblestone streets in older neighborhoods turn slick fast. A pair of genuinely waterproof, comfortable walking shoes earns its space, and a compact umbrella beats a poncho for a city built around walking rather than hiking. Outside the rainy season, both become optional rather than essential, worth throwing in anyway if you have room, but not worth planning around.
Comfortable shoes matter here beyond just the rain. This is a walkable city, and most visitors end up covering far more distance on foot each day than they would at home, moving between neighborhoods rather than driving between them. On top of that mileage, Mexico City was built on the drained bed of Lake Texcoco, and the ground under parts of the city has been sinking unevenly for decades as a result. It shows up on foot as cracked, tilted, and occasionally missing sections of sidewalk, especially in older neighborhoods, in a way flat, well-maintained streets back home do not prepare you for. A shoe with real support and a real sole earns its space here more than it would on a typical city trip.
Street vendors here announce themselves with sound instead of signs: the camote (sweet potato) cart’s high steam whistle, gas delivery trucks playing a short jingle on a loop, a recycling truck’s recorded call for old mattresses and appliances. It can start early and carry a long way, especially in residential neighborhoods. If you are a light sleeper, pack earplugs, the same way you would for a hotel with thin walls.
Mexico runs on 127 volts at 60 Hz, close enough to the US standard of 120 volts at 60 Hz that it makes no practical difference, and outlets use the same two-flat-pin Type A plug, with a Type B version adding the third round grounding pin, exactly like home. Any phone charger, laptop charger, or other electronics you already own work here without an adapter or converter, as long as the device itself is rated for something in the 100-240V range, which almost everything sold in the last decade is. The one thing worth adding is a power bank if your days will involve long excursions, a day trip, a full day of walking between neighborhoods, since a phone running maps, photos, and translation apps all day tends to run out well before you get back to a plug.
Separate anything you cannot function without, prescriptions especially, and pack it in your carry-on rather than checked luggage. It is the one packing decision that actually matters if an airline loses or delays a bag: everything else is replaceable in a pinch, a specific medication is not. For everyday items, pain relievers, allergy medication, basic first aid, do not overpack. Mexico City has pharmacies on nearly every block, and most of what you would grab at a US drugstore is easy to find here too. See Pharmacies and Common Ailments for what’s available and how to ask for it.
This one is optional, but it is what I did on my own first trips here, and I still do it. A zipper money belt worn under your clothes holds a little extra cash in pesos, a photocopy of your passport, the US Embassy’s address, your hotel or Airbnb address, and a couple of phone numbers you would actually need, all in one place that does not depend on your phone working. If your phone is ever lost, stolen, or just dies at the wrong moment, you are not stuck trying to reconstruct an address or your ID from memory. It is a small, unglamorous habit, and it has paid for itself more than once.
A day bag or backpack with an interior zippered pocket is worth the same habit. Keep extra cards or cash in that inside pocket rather than an outer one. In crowded spaces, markets, the Metro at rush hour, a packed street during a festival, an outside zipper is the first thing a pickpocket goes for, since it can be opened without you ever feeling it.
Nothing above is about avoiding attention for safety reasons. Mexico City is broadly safe in the areas and hours most visitors spend time in, and looking like a tourist does not make you a target there. If you would simply rather not look like one, for your own comfort or curiosity, the tells are more specific than most people expect.
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